Während ein Pärchen in ihrem Wohnwagen stirbt, weil ein anderes Auto in ihn reinrast, findet man in einem verdächtigen Wagen zwei Leichen im Kofferraum.

Ein Laote und sein Taxifahrer sind tot, ein weiterer Laote wird verdächtigt und noch einer ist ebenfalls tot. Unterdessen untersuchen Warrick und Greg den Tod eines Schauspielers, eindeutig wurden hier Spuren verwischt.

Ein Mann ruft erst sehr spät den Notarzt an, der kann nur noch den Tod dessen Frau feststellen. Auch seine erste Frau starb bei einem Treppensturz.

Die in einem Vorgarten abgeladene Leiche eines jungen Mannes führt Grissom direkt in das Hauptquartier einer Sekte. Dort liegen weitere elf Leichen.

Eine Familie verschwindet aus ihrem Haus, die gefundene Menge Blut lässt auf drei Leichen schließen. Nick folgt der Spur aus Kaugummibrocken, um die Tochter zu finden, während Sara im Keller eine Hanfplantage entdeckt.

Während Catherine im Mordfall einer jungen Mutter ermittelt, versucht Grissom zu beweisen, dass ein anderer Entomologe Beweise gefälscht hat.

Das Team muss den Tod eines Polizisten klären, der bei einem Einsatz im Kugelhagel ums Leben kam. Die Lage droht zu eskalieren, weil dem Team nicht nur die Feindseligkeit eines ganzen Viertels bei ihren Ermittlungen entgegenschlägt, sondern auch, weil das CSI selbst in den Fall verwickelt ist.

The CSIs continue to process the evidence collected from the high-speed chase. They must also find the bullet which killed a police officer to determine who shot him.

A man is found in a dumpster with a very full stomach. A divorcing couple are found dead together on the floor of their house, where their dog becomes the first suspect.

Eine junge Mutter behauptet, ihr Kind sei verschwunden. Als jedoch das Kind gefunden wird, stellt sich heraus, dass es gar nicht ihr Kind ist und sie psychisch krank ist.

Ein stark behaarter Mann wird mit einer Silberkugel erschossen. Es gab jedoch eine Zeugin von der niemand weiß.

The murder of a man in a garage leads the CSI team to the daughter of the man who abducted and buried Nick alive earlier.

Someone tries to kill a diva called Lois O'Neill, who was related to the mafia years ago, and a waiter is killed instead. The CSI investigates the case, but more than ever, nothing is what it seems.

A man walks into a shabby apartment and shoots the occupant. On his way home, a teenager's car crashes into his car. Ally Sullivan insists on calling the police but the man refuses. As he leaves, he sees her texting her phone. Thinking that she's calling the police, he kills her. The CSIs have a hard time finding this killer as he knows how to cover his tracks really well. He is truly a professional.

A half-naked woman is found half buried in the desert with a branding on her arm. She has no hair and is missing her right hand. The woman turns out to be Lady Heather's estranged daughter. The autopsy reveals that the woman was a victim of an experiment and starved to death. The team investigates the Betz Clinic where the deceased underwent a sleep therapy session for her insomnia.

Excessive smoke coming from a fire place alerts the fire department, which in turns calls the CSIs as a charred body is found inside the chimney. The body is burnt beyond recognition. A gym membership card found on the body identifies him as the son of the house's owner. The opportunity to search the house leads Catherine and Warrick to look for any evidence about a one-year-old disappearance of a young girl who was on her way to this house before she vanished without a trace.

Christina wurde in ihrer Wohnung vergewaltigt. Als das Team der CSI am Tatort eintrifft, treffen sie dort auf ein Kamerateam einer Reality-Show. Das Team wird die Ermittler bei ihrer Arbeit begleiten.

A teenage boy, Marlon, is being prosecuted for a murder of one of his female classmates, Stacey. During his trial, his 12-year-old sister Hannah takes the stand, and admits that she herself murdered Stacey, not Marlon. The "CSI" team is now faced with a strange dilemma - two confessions for the one murder. Collusion seems unlikely. As Hannah is a genius, in high school already, even though her confession sounds convincing, some CSI members suspect that she is making up her confession and could not have physically committed the murder. It now has to be decided who ...

Grissom, Greg und Warrick ermitteln im Fall einer Hellseherin, die erschossen wurde. Im Laufe der Ermittlungen stellt sich heraus, dass ihr Fall Verbindungen zu einem 15 Jahre alten Mord hat.

The death of three unidentified teenagers lead the CSIs inside the world of rap music.

A criminal defense lawyer is murdered at her son's wedding and tied to the back of a car with beer cans. It is later revealed that she had a bad attitude at the bride, the groom's father, and basically everyone else.

The team investigates the death of a man with a designer suit and the keys to a Ferrari, found dumped in a back alley. Their search leads them to believe he went down fighting and was dragged through a hall with wet paint on the walls. Eventually, they are led to a service in Las Vegas that orchestrates the 'perfect weekend' for an unsuspecting target by uncovering their fantasies and hiring doctors to start and play a part in those fantasies.

Mrs. Cutler is found dead, shot through the mouth, in her own home, which shows no signs of forced entry or disturbances. Her husband, Mr. William Cutler, is missing, only to be found later, alive, at his office where all of his co-workers were shot dead. He left the bloody scene with only a minor injury. All of this quickly becomes a hostage situation when Mr. Cutler, after shooting a security at a casino, holds a woman hostage.

Captain Brass kämpft um sein Leben, seine Tochter Ellie kommt. Ein dekapitierter Mann mit extrem schmaler Taille wird von einem Zug überfahren, er war Fan der Sezessionskriege.